NOW Methyl Folate 1,000mcg (90 Tablets) Quatrefolic®
NOW Methyl Folate 1,000mcg (90 Tablets) Quatrefolic®
Product Ingredients
Product Ingredients
How to Use
How to Use
FAQs
FAQs
NOW Foods Methyl Folate 1,000mcg Quatrefolic® (90 Tablets) Active Folate & Brain Health Support in Pakistan
NOW Foods Methyl Folate 1,000mcg delivers the most bioavailable form of folate using Quatrefolic® — the gold standard, patented form of (6S)-5-Methyltetrahydrofolate (5-MTHF) protected by U.S. Patent 7,947,662. Unlike regular folic acid which requires enzymatic conversion in the body, Methyl Folate is the metabolically active form that your body can use immediately — bypassing the conversion process entirely. Each tablet delivers 1,000mcg of (6S)-5-MTHF (equivalent to 1,700mcg DFE / 425% DV), providing superior bioavailability and stability compared to standard folic acid or other folate forms. Quatrefolic® is a registered trademark of Gnosis S.p.A. and has demonstrated superior bioavailability to dietary folate sources in clinical studies. Formulated by NOW Foods — a family-owned brand trusted since 1968. Available at docxora.com — Pakistan's trusted source for authentic imported NOW Foods supplements.
Imagine giving your body the exact form of folate it needs — ready to support DNA synthesis, brain health, cardiovascular wellness, and cellular energy without any conversion barriers. NOW Foods Methyl Folate with Quatrefolic® is your superior, science-backed folate supplement for optimal health, especially for those with MTHFR gene variants who cannot efficiently convert regular folic acid.
Key Benefits
Metabolically Active Folate — No Conversion Needed: 5-MTHF (Methyltetrahydrofolate) is the biologically active form of folate that bypasses the DHFR enzymatic conversion process — making it immediately usable by the body for critical metabolic functions including DNA synthesis, methylation, and neurotransmitter production. Ideal for individuals with MTHFR gene variants.
Superior Bioavailability with Quatrefolic®: Quatrefolic® is a patented, clinically studied glucosamine salt form of (6S)-5-MTHF with superior stability, solubility, and bioavailability compared to standard folic acid and other folate forms. It has demonstrated superior bioavailability to dietary folate sources in clinical research — ensuring maximum absorption and utilization.
Brain, Cognitive & Neurological Health: Methylfolate is unique in its ability to penetrate the blood-brain barrier, where it supports neurotransmitter synthesis (serotonin, dopamine, norepinephrine), healthy brain function, mood balance, mental clarity, and cognitive performance. Essential for neurological health at every age.
Cardiovascular & Homocysteine Support: Methyl Folate plays a critical role in the methylation cycle, supporting healthy homocysteine metabolism — a key factor in maintaining cardiovascular health. Elevated homocysteine is associated with cardiovascular risk, and adequate methylfolate helps keep levels in a healthy range.
DNA Synthesis, Repair & Methylation: Folate is essential for DNA synthesis, repair, and methylation — fundamental processes for healthy cell growth, division, and genetic expression. Critical during periods of rapid cell division and especially important for women of childbearing age.
MTHFR Gene Variant Support: Individuals with MTHFR (methylenetetrahydrofolate reductase) gene polymorphisms have reduced ability to convert folic acid to its active form. Methyl Folate (5-MTHF) bypasses this conversion entirely — making it the preferred folate supplement for those with MTHFR variants.
Product Highlights
| ✓ Feature | Detail |
| Methyl Folate per Tablet | 1,000mcg (6S)-5-MTHF = 1,700mcg DFE (425% DV) |
| Patented Form | Quatrefolic® (6S)-5-MTHF Glucosamine Salt — U.S. Patent 7,947,662 |
| Bioavailability | Superior to standard folic acid — Metabolically Active, No Conversion Required |
| Form | Tablets (Vegetarian & Vegan) |
| Pack Size | 90 Tablets — 3-Month Supply |
| Key Benefits | Methylation Support, Brain Health, Cardiovascular Support, DNA Synthesis, MTHFR Support, Cellular Energy |
| Certifications | Non-GMO | GMP Certified | Vegan & Vegetarian | Free from Gluten, Soy, Milk, Egg, Fish & Shellfish | NOW Foods USA (Family Owned Since 1968) |
Who Needs NOW Foods Methyl Folate?
Methyl Folate is especially beneficial for individuals with MTHFR gene variants who cannot efficiently convert regular folic acid to its active form, those seeking superior folate bioavailability with the clinically proven Quatrefolic® patented form, people focused on brain health, mood support, and cognitive performance through neurotransmitter synthesis support, individuals concerned about cardiovascular health and healthy homocysteine metabolism, women of childbearing age who need active folate for DNA synthesis and healthy cell division, vegans and vegetarians seeking a 100% plant-based B vitamin supplement, and anyone wanting a premium, science-backed folate supplement from a trusted USA brand with over 55 years of experience.
📖 Read Full Blog: NOW Methyl Folate 1000mcg Quatrefolic® – Active Folate & Brain Health Guide
How to Use NOW Foods Methyl Folate 1,000mcg
Take 1 tablet daily with a meal, or as directed by your healthcare provider. For best results, use consistently every day as part of your daily wellness routine. Do not exceed the recommended dosage. Important Caution: The elderly and individuals with conditions that may impair Vitamin B-12 absorption should frequently check Vitamin B-12 status when taking this product, as high-dose folate may mask Vitamin B-12 deficiency. Consult your healthcare provider before use if pregnant, nursing, taking medication (especially phenobarbital, phenytoin, primidone, or methotrexate), or if you have a medical condition involving nutrient malabsorption. Store in a cool, dry place below 25°C after opening. Keep out of reach of children.
Product Details
| Specification | Value |
| Brand | NOW Foods (USA) |
| Product | Methyl Folate 1,000mcg Quatrefolic® |
| Active Ingredient | Folate 1,700mcg DFE (425% DV) as 1,000mcg (6S)-5-MTHF from Quatrefolic® Glucosamine Salt |
| Other Ingredients | Microcrystalline Cellulose, Stearic Acid (vegetable source), Silicon Dioxide |
| Form | Tablets (Vegetarian & Vegan) |
| Pack Size | 90 Tablets (3-Month Supply) |
| Dietary Features | Non-GMO | Vegan & Vegetarian | Free from Wheat, Gluten, Soy, Milk, Egg, Fish, Shellfish, Tree Nuts & Sesame |
| Quality Assurance | GMP Certified Facility | Made & Quality Tested in USA with Globally Sourced Ingredients |
| Manufacturer | NOW Foods, 395 S. Glen Ellyn Rd., Bloomingdale, IL 60108, USA (Family Owned Since 1968) |
| Country of Origin | USA (with globally sourced ingredients) |
| SKU | NOW-METHYL-FOLATE-1000MCG-90TAB |
Why Shop With Us at docxora.com?
- 100% Authentic Products — directly imported from NOW Foods USA authorised distribution network
- Secure Shopping — SSL-encrypted checkout for complete peace of mind
- Fast Delivery Across Pakistan — reliable nationwide shipping to your doorstep
- Dedicated Customer Support — our team is here to help before and after your purchase
Frequently Asked Questions (FAQs)
| ❓ Question | ✅ Answer |
| What is Methyl Folate and how is it different from folic acid? | Methyl Folate (5-MTHF) is the metabolically active, biologically usable form of folate. Regular folic acid is a synthetic form that requires multiple enzymatic conversion steps in the body before it can be used. Methyl Folate bypasses this conversion entirely — making it immediately available for DNA synthesis, methylation, and neurotransmitter production, especially important for those with MTHFR gene variants. |
| What is Quatrefolic® and why is it superior? | Quatrefolic® is a patented glucosamine salt form of (6S)-5-Methyltetrahydrofolate, protected by U.S. Patent 7,947,662 and developed by Gnosis S.p.A. It has demonstrated superior bioavailability, stability, and solubility compared to standard folic acid and other folate forms in clinical studies — making it the gold standard in active folate supplementation. |
| What is MTHFR and who needs Methyl Folate? | MTHFR (methylenetetrahydrofolate reductase) is an enzyme that converts folic acid to its active form. Individuals with MTHFR gene polymorphisms (variants) have reduced enzyme activity, meaning they cannot efficiently convert regular folic acid. For these individuals, taking Methyl Folate (5-MTHF) directly bypasses this conversion barrier and ensures adequate active folate levels. |
| How long does one bottle last? | One bottle contains 90 Tablets. At the recommended dose of 1 tablet per day, one bottle provides a complete 3-month (90-day) supply — excellent value for daily folate supplementation. |
| Can Methyl Folate support brain health and mood? | Yes. Methylfolate is unique in its ability to cross the blood-brain barrier, where it supports the synthesis of key neurotransmitters including serotonin, dopamine, and norepinephrine — which play critical roles in mood regulation, mental clarity, and cognitive performance. Adequate methylfolate is essential for neurological health. |
| Is Methyl Folate important for cardiovascular health? | Yes. Methyl Folate is a key nutrient in the methylation cycle that helps regulate homocysteine levels in the blood. Elevated homocysteine is associated with increased cardiovascular risk. Adequate methylfolate helps maintain healthy homocysteine metabolism, supporting overall cardiovascular wellness. |
| Is there any caution regarding Vitamin B-12? | Yes. High-dose folate supplementation may mask Vitamin B-12 deficiency symptoms. The elderly and individuals with conditions that impair B-12 absorption should regularly monitor their Vitamin B-12 status when taking this product. Consider pairing with a Vitamin B-12 supplement if needed — consult your healthcare provider. |
| Is this product suitable for vegans? | Yes. NOW Foods Methyl Folate tablets are 100% plant-based and vegan-friendly. The tablet contains only Microcrystalline Cellulose, Stearic Acid (vegetable source), and Silicon Dioxide — all vegan-compatible ingredients. No animal-derived ingredients are used. |
| Is this product authentic and available in Pakistan? | Yes. Available exclusively at docxora.com — directly imported from NOW Foods USA authorised distribution network. 100% authentic, guaranteed genuine supplement. |
| How should I store this product? | Store in a cool, dry place below 25°C away from direct sunlight and moisture after opening. Keep out of reach of children. Do not use if the seal is broken upon purchase. Natural color variation may occur in this product. |
Medical Disclaimer:
The information provided here is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting any new supplement.
docxora.com is not the manufacturer of the products sold on our website.
Always read the labels, warnings, and instructions provided with the product before use.
📖 Read Full Blog: NOW Methyl Folate 1000mcg Quatrefolic® – Active Folate & Brain Health Guide
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