NOW Foods SAMe 400mg (30 Tablets)
NOW Foods SAMe 400mg (30 Tablets)
Product Ingredients
Product Ingredients
How to Use
How to Use
FAQs
FAQs
NOW Foods SAMe 400mg (30 Tablets)NOW Foods SAMe 400mg – Stabilized S-Adenosyl-L-Methionine for Nervous System, Joint & Liver Health in Pakistan
Overview
Introducing NOW Foods SAMe 400mg delivers a high-potency dose of S-Adenosyl-L-Methionine (SAMe) — the body's primary methyl donor — in a stabilized form requiring no enteric coating, resulting in a smaller, easier-to-swallow tablet. Each tablet provides 400mg of SAMe (from S-Adenosyl-L-Methionine Disulfate Tosylate) to support nervous system function, joint health, liver detoxification, and mood. Manufactured in GMP-certified USA facilities by NOW Foods — a family-owned brand trusted since 1968. Available at docxora.com — Pakistan's trusted source for authentic imported supplements.
Why Choose NOW Foods SAMe 400mg?
Imagine a single molecule that touches nearly every system in your body — from your mood and mental clarity to your joint comfort and liver health. NOW Foods SAMe 400mg harnesses the power of this remarkable compound, supporting neurotransmitter synthesis, cartilage integrity, and methylation pathways — all in one small, stabilized tablet that your body can actually absorb.
Key Benefits
Nervous System & Mood Support
SAMe is a critical precursor in the synthesis of serotonin, dopamine, and norepinephrine — the neurotransmitters that regulate mood, motivation, and emotional wellbeing. By supporting healthy methylation, SAMe helps maintain optimal neurotransmitter levels and nervous system function.
Joint Health & Cartilage Support
SAMe plays a direct role in the synthesis of proteoglycans — essential structural components of joint cartilage. Research supports SAMe's ability to maintain healthy cartilage integrity and joint comfort, making it a well-studied natural option for joint health support.
Liver Health & Detoxification
SAMe is essential for glutathione synthesis — the body's master antioxidant and primary liver detoxification molecule. It supports healthy liver cell membrane function and the liver's ability to process and eliminate toxins.
Methylation Support
As the body's primary methyl donor, SAMe participates in over 100 biochemical methylation reactions — including DNA methylation, gene expression regulation, and the metabolism of hormones, neurotransmitters, and phospholipids.
Stabilized Formula — No Enteric Coating Needed
NOW Foods uses S-Adenosyl-L-Methionine Disulfate Tosylate — a stabilized salt form that maintains potency and bioavailability without requiring an enteric coating. This allows for a smaller, more convenient tablet that is easier to swallow.
GMP Certified USA Manufacturing
Made and quality tested in the USA with globally sourced ingredients. Not manufactured with wheat, gluten, soy, milk, egg, fish, or shellfish ingredients. Produced in a GMP-certified facility.
Product Highlights
| ✓ Feature | Detail |
|---|---|
| Brand | NOW Foods (USA, since 1968) |
| Active Ingredient | SAMe (S-Adenosyl-L-Methionine) 400mg per tablet |
| SAMe Form | S-Adenosyl-L-Methionine Disulfate Tosylate (Stabilized) |
| Key Feature | Stabilized SAMe — No Enteric Coating Needed |
| Serving Size | 1 Tablet daily |
| Pack Size | 30 Tablets (1-month supply) |
| Dietary Features | No wheat, gluten, soy, milk, egg, fish, or shellfish |
| Quality Assurance | GMP Certified, Quality Tested in USA |
| Country of Origin | USA |
Who Needs SAMe 400mg?
NOW Foods SAMe 400mg is ideal for individuals seeking mood and nervous system support, those with joint discomfort looking for a natural cartilage support supplement, people supporting liver health and detoxification, individuals with methylation concerns (including those with MTHFR variants), and anyone looking for a comprehensive, multi-system support supplement backed by decades of research. Suitable for adults seeking natural wellness support.
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How to Use NOW Foods SAMe 400mg
Take 1 tablet daily on an empty stomach, preferably 30 minutes before a meal, or as directed by your healthcare practitioner. Do not take in the evening as it may be stimulating. Do not exceed the recommended daily dose. Consult your physician before use if taking antidepressants, MAO inhibitors, or any medications. Not recommended for pregnant or nursing women or individuals with bipolar disorder without physician supervision.
Product Details
| Specification | Value |
|---|---|
| Brand | NOW Foods |
| Product | SAMe 400mg (S-Adenosyl-L-Methionine) |
| Active Ingredient | SAMe (S-Adenosyl-L-Methionine Disulfate Tosylate) 400mg |
| Other Ingredients | Microcrystalline Cellulose, Stearic Acid (vegetable source), Pharmaceutical Glaze, Magnesium Stearate (vegetable source), Silicon Dioxide, Glycerin, Sodium Alginate, L-Arginine |
| Form | Tablet (Stabilized, No Enteric Coating) |
| Pack Size | 30 Tablets |
| Dietary Features | No wheat, gluten, soy, milk, egg, fish, or shellfish |
| Quality Assurance | GMP Certified, Quality Tested in USA |
| Manufacturer | NOW Foods, 395 S. Glen Ellyn Rd., Bloomingdale, IL 60108, USA |
| Country of Origin | USA |
| SKU | NOW-SAME-400MG-30TAB |
Why Shop With Us at docxora.com?
- 100% Authentic Products — directly imported from NOW Foods authorised distribution network
- Secure Shopping — SSL-encrypted checkout
- Fast Delivery Across Pakistan — reliable nationwide shipping
- Dedicated Customer Support — here to help before and after your purchase
Frequently Asked Questions (FAQs)
| ❓ Question | ✅ Answer |
|---|---|
| What is SAMe? | S-Adenosyl-L-Methionine — the body's primary methyl donor, involved in 100+ biochemical reactions supporting mood, joints, liver, and methylation. |
| What does SAMe support? | Nervous system & mood (neurotransmitter synthesis), joint cartilage integrity, liver detoxification (glutathione synthesis), and DNA methylation. |
| Why no enteric coating? | NOW uses stabilized SAMe Disulfate Tosylate — a form that maintains potency without enteric coating, resulting in a smaller, easier-to-swallow tablet. |
| When should I take it? | 1 tablet daily on an empty stomach, 30 minutes before a meal. Avoid evening dosing as it may be stimulating. |
| How long does one bottle last? | 30 tablets at 1/day = 30-day (1-month) supply. |
| Can I take it with antidepressants? | Consult your physician before use if taking antidepressants, MAO inhibitors, or any medications. Not for use with bipolar disorder without supervision. |
| Does it support joint health? | Yes. SAMe supports proteoglycan synthesis — key structural components of joint cartilage — and is well-researched for joint comfort and mobility. |
| Is NOW Foods trusted? | Yes. Family-owned since 1968, GMP-certified USA facilities, rigorous third-party quality testing. |
| Is this product authentic? | Yes. docxora.com imports directly from NOW Foods authorised distribution network. 100% authentic, quality tested in USA. |
| How to store? | Store in a cool, dry place. Keep container tightly closed. Keep out of reach of children. Natural color variation may occur. |
Medical Disclaimer:
The information provided here is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider or doctor in Pakistan before starting any new supplement.
docxora.com is not the manufacturer of the products sold on our website.
Always read the labels, warnings and instructions provided with the product before using or consuming it.
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Shipping & Rerturns
Shipping & Rerturns
• Shipping: Orders are processed within 1–2 business days. Standard delivery takes 3–7 business days depending on your location.
• Returns: You may return or exchange products within 30 days of receiving your order. Items must be in original condition with proof of purchase.
If your item is defective or damaged due to manufacturing issues, we’ll gladly replace it at no additional cost.
Discover more in our FAQ
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How long does it take to process an order?
How long does it take to process an order?
Orders are typically processed within 1–2 business days. You will receive a confirmation email with tracking details once your order has been shipped. Please note that processing times may be slightly longer during high-demand periods or sales events.
What kind of products does Docxora offer?
What kind of products does Docxora offer?
Docxora provides a curated selection of health and wellness essentials, including vitamins, herbal supplements, skincare, and baby care products sourced from trusted global brands and backed by research.
What is your return policy?
What is your return policy?
We accept returns within 7 days of delivery. To be eligible, items must be unused, in their original packaging, and accompanied by proof of purchase. If the item is faulty or damaged, we will cover the return shipping and provide a replacement or full refund.
Are the products on Docxora safe and reliable?
Are the products on Docxora safe and reliable?
Absolutely. We handpick every item with care, working only with reputable suppliers. Each product is chosen based on quality, effectiveness, and customer trust so you can shop confidently.