{"product_id":"now-foods-same-400mg-30-tablets","title":"NOW Foods SAMe 400mg (30 Tablets)","description":"\u003ch1 style=\"color: #2b00ff;\"\u003e\u003cstrong\u003eNOW Foods SAMe 400mg (30 Tablets)NOW Foods SAMe 400mg – Stabilized S-Adenosyl-L-Methionine for Nervous System, Joint \u0026amp; Liver Health in Pakistan\u003c\/strong\u003e\u003c\/h1\u003e\n\u003ch2\u003eOverview\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eIntroducing  \u003c\/span\u003e\u003cstrong\u003eNOW Foods\u003c\/strong\u003e \u003cstrong\u003eSAMe 400mg\u003c\/strong\u003e delivers a high-potency dose of \u003cstrong\u003eS-Adenosyl-L-Methionine (SAMe)\u003c\/strong\u003e — the body's primary methyl donor — in a \u003cstrong\u003estabilized form requiring no enteric coating\u003c\/strong\u003e, resulting in a smaller, easier-to-swallow tablet. Each tablet provides \u003cstrong\u003e400mg of SAMe\u003c\/strong\u003e (from S-Adenosyl-L-Methionine Disulfate Tosylate) to support \u003cstrong\u003enervous system function, joint health, liver detoxification, and mood\u003c\/strong\u003e. Manufactured in \u003cstrong\u003eGMP-certified USA facilities\u003c\/strong\u003e by NOW Foods — a family-owned brand trusted since 1968. Available at \u003cstrong\u003edocxora.com\u003c\/strong\u003e — Pakistan's trusted source for authentic imported supplements.\u003c\/p\u003e\n\u003ch2\u003eWhy Choose NOW Foods SAMe 400mg?\u003c\/h2\u003e\n\u003cp\u003eImagine a single molecule that touches nearly every system in your body — from your mood and mental clarity to your joint comfort and liver health. \u003cstrong\u003eNOW Foods SAMe 400mg\u003c\/strong\u003e harnesses the power of this remarkable compound, supporting \u003cstrong\u003eneurotransmitter synthesis, cartilage integrity, and methylation pathways\u003c\/strong\u003e — all in one small, stabilized tablet that your body can actually absorb.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eNervous System \u0026amp; Mood Support\u003c\/strong\u003e\u003cbr\u003eSAMe is a critical precursor in the synthesis of \u003cstrong\u003eserotonin, dopamine, and norepinephrine\u003c\/strong\u003e — the neurotransmitters that regulate mood, motivation, and emotional wellbeing. By supporting healthy methylation, SAMe helps maintain optimal neurotransmitter levels and nervous system function.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eJoint Health \u0026amp; Cartilage Support\u003c\/strong\u003e\u003cbr\u003eSAMe plays a direct role in the synthesis of \u003cstrong\u003eproteoglycans\u003c\/strong\u003e — essential structural components of joint cartilage. Research supports SAMe's ability to maintain healthy cartilage integrity and joint comfort, making it a well-studied natural option for joint health support.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eLiver Health \u0026amp; Detoxification\u003c\/strong\u003e\u003cbr\u003eSAMe is essential for \u003cstrong\u003eglutathione synthesis\u003c\/strong\u003e — the body's master antioxidant and primary liver detoxification molecule. It supports healthy liver cell membrane function and the liver's ability to process and eliminate toxins.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMethylation Support\u003c\/strong\u003e\u003cbr\u003eAs the body's primary methyl donor, SAMe participates in over \u003cstrong\u003e100 biochemical methylation reactions\u003c\/strong\u003e — including DNA methylation, gene expression regulation, and the metabolism of hormones, neurotransmitters, and phospholipids.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStabilized Formula — No Enteric Coating Needed\u003c\/strong\u003e\u003cbr\u003eNOW Foods uses \u003cstrong\u003eS-Adenosyl-L-Methionine Disulfate Tosylate\u003c\/strong\u003e — a stabilized salt form that maintains potency and bioavailability without requiring an enteric coating. This allows for a \u003cstrong\u003esmaller, more convenient tablet\u003c\/strong\u003e that is easier to swallow.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eGMP Certified USA Manufacturing\u003c\/strong\u003e\u003cbr\u003eMade and quality tested in the USA with globally sourced ingredients. Not manufactured with wheat, gluten, soy, milk, egg, fish, or shellfish ingredients. Produced in a GMP-certified facility.\u003c\/p\u003e\n\u003ch2\u003eProduct Highlights\u003c\/h2\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse;\"\u003e\n\u003cthead\u003e\n\u003ctr style=\"background-color: #f47920; color: #ffffff;\"\u003e\n\u003cth style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003e✓ Feature\u003c\/th\u003e\n\u003cth style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eDetail\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr style=\"background-color: #fff8f3;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eBrand\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eNOW Foods (USA, since 1968)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #ffffff;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eActive Ingredient\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eSAMe (S-Adenosyl-L-Methionine) 400mg per tablet\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #fff8f3;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eSAMe Form\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eS-Adenosyl-L-Methionine Disulfate Tosylate (Stabilized)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #ffffff;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eKey Feature\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eStabilized SAMe — No Enteric Coating Needed\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #fff8f3;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eServing Size\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003e1 Tablet daily\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #ffffff;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003ePack Size\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003e30 Tablets (1-month supply)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #fff8f3;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eDietary Features\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eNo wheat, gluten, soy, milk, egg, fish, or shellfish\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #ffffff;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eQuality Assurance\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eGMP Certified, Quality Tested in USA\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #fff8f3;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eCountry of Origin\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eUSA\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2\u003eWho Needs SAMe 400mg?\u003c\/h2\u003e\n\u003cp\u003eNOW Foods SAMe 400mg is ideal for \u003cstrong\u003eindividuals seeking mood and nervous system support\u003c\/strong\u003e, \u003cstrong\u003ethose with joint discomfort\u003c\/strong\u003e looking for a natural cartilage support supplement, \u003cstrong\u003epeople supporting liver health and detoxification\u003c\/strong\u003e, \u003cstrong\u003eindividuals with methylation concerns\u003c\/strong\u003e (including those with MTHFR variants), and anyone looking for a \u003cstrong\u003ecomprehensive, multi-system support supplement\u003c\/strong\u003e backed by decades of research. Suitable for adults seeking natural wellness support.\u003c\/p\u003e\n\u003cp style=\"text-align: center; margin: 20px 0;\"\u003e\u003ca href=\"https:\/\/www.docxora.com\/blogs\/news\" style=\"background-color: #1a73e8; color: #ffffff; padding: 12px 28px; text-decoration: none; border-radius: 6px; font-weight: bold; font-size: 15px;\" target=\"_blank\"\u003e📖 Read Our Health \u0026amp; Supplement Blog\u003c\/a\u003e\u003c\/p\u003e\n\u003ch2\u003eHow to Use NOW Foods SAMe 400mg\u003c\/h2\u003e\n\u003cp\u003eTake \u003cstrong\u003e1 tablet daily on an empty stomach\u003c\/strong\u003e, preferably 30 minutes before a meal, or as directed by your healthcare practitioner. Do not take in the evening as it may be stimulating. Do not exceed the recommended daily dose. Consult your physician before use if taking antidepressants, MAO inhibitors, or any medications. Not recommended for pregnant or nursing women or individuals with bipolar disorder without physician supervision.\u003c\/p\u003e\n\u003ch2\u003eProduct Details\u003c\/h2\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse;\"\u003e\n\u003cthead\u003e\n\u003ctr style=\"background-color: #2c2c2c; color: #ffffff;\"\u003e\n\u003cth style=\"padding: 10px; border: 1px solid #e0e0e0;\"\u003eSpecification\u003c\/th\u003e\n\u003cth style=\"padding: 10px; border: 1px solid #e0e0e0;\"\u003eValue\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr style=\"background-color: #f9f9f9;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #e0e0e0;\"\u003eBrand\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #e0e0e0;\"\u003eNOW Foods\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #ffffff;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #e0e0e0;\"\u003eProduct\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #e0e0e0;\"\u003eSAMe 400mg (S-Adenosyl-L-Methionine)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #f9f9f9;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #e0e0e0;\"\u003eActive Ingredient\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #e0e0e0;\"\u003eSAMe (S-Adenosyl-L-Methionine Disulfate Tosylate) 400mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #ffffff;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #e0e0e0;\"\u003eOther Ingredients\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #e0e0e0;\"\u003eMicrocrystalline Cellulose, Stearic Acid (vegetable source), Pharmaceutical Glaze, Magnesium Stearate (vegetable source), Silicon Dioxide, Glycerin, Sodium Alginate, L-Arginine\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #f9f9f9;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #e0e0e0;\"\u003eForm\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #e0e0e0;\"\u003eTablet (Stabilized, No Enteric Coating)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #ffffff;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #e0e0e0;\"\u003ePack Size\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #e0e0e0;\"\u003e30 Tablets\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #f9f9f9;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #e0e0e0;\"\u003eDietary Features\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #e0e0e0;\"\u003eNo wheat, gluten, soy, milk, egg, fish, or shellfish\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #ffffff;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #e0e0e0;\"\u003eQuality Assurance\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #e0e0e0;\"\u003eGMP Certified, Quality Tested in USA\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #f9f9f9;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #e0e0e0;\"\u003eManufacturer\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #e0e0e0;\"\u003eNOW Foods, 395 S. Glen Ellyn Rd., Bloomingdale, IL 60108, USA\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #ffffff;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #e0e0e0;\"\u003eCountry of Origin\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #e0e0e0;\"\u003eUSA\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #f9f9f9;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #e0e0e0;\"\u003eSKU\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #e0e0e0;\"\u003eNOW-SAME-400MG-30TAB\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2\u003eWhy Shop With Us at docxora.com?\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e100% Authentic Products\u003c\/strong\u003e — directly imported from NOW Foods authorised distribution network\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSecure Shopping\u003c\/strong\u003e — SSL-encrypted checkout\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFast Delivery Across Pakistan\u003c\/strong\u003e — reliable nationwide shipping\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDedicated Customer Support\u003c\/strong\u003e — here to help before and after your purchase\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eFrequently Asked Questions (FAQs)\u003c\/h2\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse;\"\u003e\n\u003cthead\u003e\n\u003ctr style=\"background-color: #f47920; color: #ffffff;\"\u003e\n\u003cth style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003e❓ Question\u003c\/th\u003e\n\u003cth style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003e✅ Answer\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr style=\"background-color: #fff8f3;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eWhat is SAMe?\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eS-Adenosyl-L-Methionine — the body's primary methyl donor, involved in 100+ biochemical reactions supporting mood, joints, liver, and methylation.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #ffffff;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eWhat does SAMe support?\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eNervous system \u0026amp; mood (neurotransmitter synthesis), joint cartilage integrity, liver detoxification (glutathione synthesis), and DNA methylation.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #fff8f3;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eWhy no enteric coating?\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eNOW uses stabilized SAMe Disulfate Tosylate — a form that maintains potency without enteric coating, resulting in a smaller, easier-to-swallow tablet.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #ffffff;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eWhen should I take it?\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003e1 tablet daily on an empty stomach, 30 minutes before a meal. Avoid evening dosing as it may be stimulating.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #fff8f3;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eHow long does one bottle last?\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003e30 tablets at 1\/day = 30-day (1-month) supply.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #ffffff;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eCan I take it with antidepressants?\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eConsult your physician before use if taking antidepressants, MAO inhibitors, or any medications. Not for use with bipolar disorder without supervision.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #fff8f3;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eDoes it support joint health?\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eYes. SAMe supports proteoglycan synthesis — key structural components of joint cartilage — and is well-researched for joint comfort and mobility.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #ffffff;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eIs NOW Foods trusted?\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eYes. Family-owned since 1968, GMP-certified USA facilities, rigorous third-party quality testing.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #fff8f3;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eIs this product authentic?\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eYes. docxora.com imports directly from NOW Foods authorised distribution network. 100% authentic, quality tested in USA.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #ffffff;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eHow to store?\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #f0d5c0;\"\u003eStore in a cool, dry place. Keep container tightly closed. Keep out of reach of children. Natural color variation may occur.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eMedical Disclaimer:\u003c\/strong\u003e\u003cbr\u003eThe information provided here is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider or doctor in Pakistan before starting any new supplement.\u003cbr\u003edocxora.com is not the manufacturer of the products sold on our website.\u003cbr\u003eAlways read the labels, warnings and instructions provided with the product before using or consuming it.\u003c\/em\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: center; margin: 20px 0;\"\u003e\u003ca href=\"https:\/\/www.docxora.com\/blogs\/news\" style=\"background-color: #1a73e8; color: #ffffff; padding: 12px 28px; text-decoration: none; border-radius: 6px; font-weight: bold; font-size: 15px;\" target=\"_blank\"\u003e📖 Read Our Health \u0026amp; Supplement Blog\u003c\/a\u003e\u003c\/p\u003e","brand":"NOW Foods","offers":[{"title":"Default Title","offer_id":49135286223071,"sku":"NOW-SAME-400MG-30TAB","price":12500.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0738\/8751\/4847\/files\/29_2.avif?v=1784728090","url":"https:\/\/www.docxora.com\/products\/now-foods-same-400mg-30-tablets","provider":"Docxora","version":"1.0","type":"link"}